I went to Nepal last year as part of a group tour. I was armed with this guide in order to do some exploring on my own in Kathmandu & Pokhara, and to have the right background for hiking a few days along the Annapurna trek. Wherever I go, the Rough Guide is usually my first choice as it contains a well-balanced mix of background info, dependable information on hotels/restaurants/transportation, fantastic topic-related inserts (e.g., the people of Nepal), and good pictures of the top attractions. For example, I was very happy when I visited several UNESCO World Heritage sites in Nepal - the Rough Guide came in very handy with its detailed descriptions of walking routes and associated maps (no local guide was necessary).
The book has two major shortcomings, though. First, trek descriptions are very brief, and not very informative with regard to the villages and its amenities/restaurants that you come across (idea: maybe the guide should be split in two books, general/culture vs. trekking). Second, the maps of Kathmandu do not capture the complexity and size of this city.
Overall, not a bad guide, but not delivering the depth I am used to in the Rough Guide series.